PS2 Mouse and USB keyboard? in Processors, Motherboards and Memory Posted January 28, 2006 I am using a USB Keytronics keyboard and a PS/2 Kensington Expert Mouse trackball. When I tried using the Kensington trackball directly without the PS/2 adapter, I got about a 50% response rate after reboots: half the time the USB mouse was not detected. This led me to use the PS/2 adapter for the trackball, which resolved that particular issue. There are still problems detecting the Keytronics USB keyboard if I reset the BIOS, so really the MOBO/BIOS still likes to see PS/2 devices rather than USB. I also have problems leaving my Dazzle 8-1 USB 2.0 card adapter plugged in. I've just learned to not trust USB devices, it's not only a DFI problem.