Yeah, sounds like he's talking about the old school frames.... which IMO is the bane of the internet, and should not be used anymore. With a frame or without a frame, you're going to be sending a request to load an entire page, so I don't see why he only wants one section to "reload".
Anyway... give the frame a name, and then have the target of the URL set as the name for the frame.
<a href="whateverpage.html" target="main">This like</a>
Would open "whateverpage.html" in the frame named "main".