It can absolutely kill your mobo, don't listen to people saying otherwise. I don't know the standard FSB for your motherboard but there's a line where if it is too high - it won't boot and go into BSOD and a little lower - it will still work. If this safe value is ~10% higher than your standard FSB - it's going to be fine. What if it's 50%? You'll need a really good cooling on your mobo and airflow in the case because otherwise, you'll burn it in a few months of such stress. It's almost the same as overclocking your RAM or CPU. Yeah, you can make your 1.6V RAM work on 2.0V and +400-600-800 Mhz by some miracle, but for how long it will last?